The Times Literary Supplement (or TLS, on the front page from 1969) is a weekly literary review published in London by News International, a subsidiary of News Corporation.

It first appeared in 1902 as a supplement to The Times, but became a separate publication in 1914. Many distinguished writers have been contributors, including T. S. Eliot, Henry James, and Virginia Woolf, but reviews were normally anonymous until 1974, during which year signed reviews were gradually introduced. Martin Amis was a member of the editorial staff early in his career. Philip Larkin's poem Aubade, effectively his final poetic work, was first published in the Christmas-week issue of the TLS in 1977. While it has long been regarded as one of the world's pre-eminent critical publications, its history is not without gaffes. For instance, the publication missed James Joyce entirely.

The TLS cooperates closely with The Times; its online version is hosted on The Times website and its editorial offices are based in the Times House, Pennington Street, London. The current editor is Peter Stothard, a former editor of The Times itself. He succeeded Ferdinand Mount in 2003.