"The Simpsons Theme", also referred to "The Simpsons Main Title Theme" in album releases, is the theme song of the animated television series The Simpsons. It plays during the opening sequence and was composed by Danny Elfman in 1989, after series creator Matt Groening approached him requesting a retro-style theme. The piece, which took two days to create, has been noted by Elfman as the most popular of his career. . The theme as used for the opening sequence has been edited many times to coincide with edits of various lengths for the opening sequence. In addition, there have been extended edits and re-recordings for lengthened opening sequences. Several versions of the saxophone solo riff, ostensibly played by Lisa Simpson in the animated sequence, have been created over the course of the series. A slightly different arrangement of the theme usually plays over the end credits of the show.

The first and third notes beginning the theme form an augmented fourth, known as a tritone, and the fact that this interval is shared in common with many pieces of heavy metal music is often cited in articles on the topic .