The Jump Off is the first single off the multi-platinum album La Bella Mafia. The single debuted at number 95 and climbed into the top 20 at # 16. The single sold over 200,000 copies and certified platinum within months. A remix was also released but was used as a promotional single.

The song is produced by well-known hip-hop producer Timbaland and features Mr. Cheeks for background vocals.