The Brak Show was an animated series consisting of 15-minute episodes on the Cartoon Network that aired during Adult Swim. The show was a spin-off of Space Ghost: Coast to Coast, and featured recurring characters from that show and Cartoon Planet. Both programs used stock footage from the Hanna-Barbera cartoon Space Ghost and Dino-Boy. The protagonist is a Space Ghost villain named "Brak", voiced by Andy Merrill, who developed a quirky persona for the character.

The Brak Show was preceded by two specials entitled Brak Presents The Brak Show Starring Brak. Despite the similarities in the titles, the two Brak Shows have very little in common. The latter show was a spoof of early sitcoms, while the former parodied the genre of variety shows. Both of the episodes aired in the US only once in 2000, although clips of the show could be viewed after the Space Ghost Coast to Coast time slot on occasion. In the UK only one of the two specials aired on Bravo on August 23, 2006 and then again on December 23, 2007. There are also clips from the shows on The Brak Show Volume 1 DVD and AdultSwim.com.

The Brak Show series premiered unannounced in the early hours of December 21, 2000, along with the "Radio Free Sealab" episode of Sealab 2021. This "stealth" pilot (titled "Leave it to Brak") featured hand-drawn backgrounds and different opening titles. The show's second showing was on Adult Swim's debut on September 2, 2001. As with most of the first original Adult Swim shows it was produced by Williams Street Studios.

The show is about Brak's suburban life with his alien mother and Cuban father. It originally started off as a parody of situation comedies, but just like its sister show, Aqua Teen Hunger Force, the plot dissolved over time and became increasingly bizarre. The setting is suburbia with an extra-planetary hint. A Saturn-like planet appears in the background on occasion, and many of the extras are aliens.

The show was canceled in December of 2003. However, Adult Swim announced in a bump on October 22, 2006 that, The Brak Show would return to production as an internet cartoon on the network's website. On May 24, 2007, a new webisode premiered online, but was later removed.

"The Brak Show is a story of a neighborhood. It's the story of a family. It's the story of what happens when adults have children and those children go to school. And Brak is in it. He lives in a house. A house on a quiet street not unlike yours or mine. A house in a neighborhood. That's The Brak Show." So goes Cartoon network's description of the new sitcom starring Brak, the absent-minded space pirate from the Space Ghost cartoons. He goes through the all the typical sitcom situations with his friend Zorak. Also along for the ride are Brak's parents, his brother Sisto, and his next-door neighbor Thundercleese. Written by Joe Cassidy