The Bourne Supremacy is the second Jason Bourne novel written by Robert Ludlum, first published in 1986. It was the sequel to Ludlum's bestseller The Bourne Identity (1980) and precedes Ludlum's final Bourne novel, The Bourne Ultimatum (1990).

The Bourne Supremacy was adapted into a film of the same name in 2004 starring Matt Damon, although the film has a completely distinct (and contradictory) plot to the novel.