Blues is a vocal and instrumental form of music based on the use of the blue notes. It emerged in African-American communities of the United States from spirituals, work songs, field hollers, shouts and chants, and rhymed simple narrative ballads. The use of blue notes and the prominence of call-and-response patterns in the music and lyrics are indicative of African influence. The blues influenced later American and Western popular music, as it became the roots of jazz, bluegrass, rhythm and blues, rock and roll, heavy metal music, hip-hop, and other popular music forms.

The ghost that Jr. saw of W.C. Handy was played by his own father, Nathaniel Lee Sr.