The Space Shuttle Challenger disaster took place when Challenger, a Space Shuttle operated by NASA, broke apart 73 seconds into its flight leading to the deaths of its seven crew members. The spacecraft disintegrated over the Atlantic Ocean, off the coast of central Florida, United States at 11:39 a.m. EST (16:39 UTC) on January 28 1986. Disintegration of the shuttle stack began 73 seconds into its flight after an O-ring seal in its right solid rocket booster (SRB) failed at liftoff. The seal failure caused a breach in the SRB joint it filled, allowing a flare to reach the outside and impinge upon the adjacent attachment hardware and external fuel tank. The SRB breach flare led to the separation of the right-hand SRB and the structural failure of the external tank. Aerodynamic forces promptly broke up the orbiter. The shuttle was destroyed and all seven crew members were killed. The crew compartment and many other vehicle fragments were eventually recovered from the ocean floor after a lengthy search and recovery operation.

The disaster resulted in a 32-month hiatus in the shuttle program and the formation of the Rogers Commission, a special commission appointed by United States President Ronald Reagan to investigate the accident. The Rogers Commission found that NASA's organizational culture and decision-making processes had been a key contributing factor to the accident. NASA managers had known that contractor Morton Thiokol's design of the SRBs contained a potentially catastrophic flaw in the O-rings since 1977, but they failed to address it properly. They also ignored warnings from engineers about the dangers of launching on such a cold day and had failed to adequately report these technical concerns to their superiors. The Rogers Commission offered NASA nine recommendations that were to be implemented before shuttle flights resumed.

Many viewed the launch live due to the presence on the crew of Christa McAuliffe, the first member of the Teacher in Space Project. Media coverage of the accident was extensive: one study reported that 85 percent of Americans surveyed had heard the news within an hour of the accident. The Challenger disaster has been used as a case study in many discussions of engineering safety and workplace ethics and inspired the 1990 television movie, Challenger.