Sister, Sister is an American television sitcom about twin girls (Tia and Tamera Mowry), separated and adopted at birth, who one day come face-to-face after 14 years apart. The series premiered during the 1993-94 season on ABC, briefly canceled after the 1994-95 season; but The WB re-newed the show for the 1995-96 season, continuing until May 23, 1999.

Sister, Sister is a 1982 TV movie that stars Diahann Carroll, Rosalind Cash, and Irene Cara. It was written by Maya Angelou.

Sister, Sister is a 1987 Southern Gothic thriller directed and co-written by Bill Condon. The film stars Eric Stoltz, Jennifer Jason Leigh, and Judith Ivey.

Maya Angelou's story of the family stresses that occur when an older sister (Diahann Carroll) attempts to maintain a home, left by her revered father, in an ultra-moralistic way (regardless of the fact that she is secretly having an affair with the married preacher). Nevertheless, her uptight need to maintain a sense of propriety of course goes against the wishes of her much younger sister (Irene Cara) who, as an accomplished ice skater, is striving for her own independence. And if this isn't enough, into it is suddenly thrust a third sister (Rosalind Cash), who is a single mother with a pre-teen son, who "comes home" with her boy after living for years in the ghettos of Detroit. And because she is the complete antithesis of her older sister in morals and deportment, she immediately sides with her younger sister against the strictures set down in the home. Written by BOB STEBBINS

Matt Rutledge (Eric Stoltz) is on buisness in the country. He decides to stay at an old house which is a bed-in-breakfast type of place owned by two sisters, Charlotte (Judith Ivey) and Lucy (Jennifer Jason Leigh). Charlotte is in and out of love with town sheriff, Cleve Doucet (Dennis Lipscomb) while Lucy becomes seductive and attracted to Matt. Written by Anonymous

Tia and Tamera Mowry play twins who were separated at birth and by chance meet each other in a shopping mall. Ray Campbell, Tamera's adopted father, is very different from Tia's adopted mother, Lisa Landry, but the twins don't want to be separated so Ray and Lisa end up living together. The series often focuses on the trouble the twins get into due to their identical appearance and the love-hate relationship between Lisa and Ray. Written by Ondre Lombard