Sean John is a clothing line founded by hip-hop mogul Sean Combs A.K.A Sean John, in 1998. The name is taken from Combs' first and middle given names.

People representing the brand include Combs himself, rappers T.I. (whos a hip-hop rap artist), Fabolous(whos a hip-hop rap artist), The Game(whos a hip-hop rap artist), Daddy Yankee (whos a Reggaeton star), basketball stars Dwyane Wade and Tristan Sooklal, and models Tyson Beckford and Kevin Navayne.

In October 2003 P. Diddy was under intense media attention for using sweatshop labor to produce his clothing line. Among the accusations, originally put forth by the National Labor Committee (NLC), workers were subjected to body searches, fired if pregnant and paid sweatshop wages. Diddy responded to the BBC that there would be a "zero tolerance" investigation at his company, Sean John. He stated to a group of reporters "I'm as pro-worker as they get."

In 2005 and 2006 his clothing line, Sean John, was again the center of debate due to the fact that it outsourced its labor and forced workers to work nearly 14 hour shifts. The workers, mostly comprised of teenage girls, got paid an average of 15 cents per hour under horrible conditions. Most of the workers were denied bathroom breaks, the right to talk to each other, and forced to buy meals from the factory, which caused many of them to end their work day in debt.

In 2006, Sean John also launched its first fragrance, a men's scent called Unforgivable manufactured by Estée Lauder.

In late 2006, after allegations of raccoon dog fur being used in two styles of jackets, Sean John, together with Macy's, pulled all of the garments from the department stores where this product was shipped.

Cassie and Lauren London are spokesmodels for the Sean John women's collection, which Diddy said would be released in July 2007.