Project Helix is the name of a fictional technology in the TV series Alias. The device is used to rewrite a person's DNA, effectively morphing them into a clone of the person from whom the replacement DNA was procured. The only way to detect a double is through a deliberate flaw built into the process, detectable by an ocular scan. It is unknown whether the process is reversible.

Since its creation, there have been three known and two possible subjects of Project Helix: