A perforation in the context of oil wells, refers to a hole punched in the casing or liner of an oil well to connect it to the reservoir. In cased hole completions, the well will be drilled down past the section of the formation desired for production and will have casing or a liner run in separating the formation from the well bore. The final stage of the completion will involve running in perforating guns, a string of shaped charges, down to the desired depth and firing them to perforate the casing or liner. A typical perforating gun can carry many dozens of charges.

Commonly, perforation guns are run on E-line as it is traditional to use electrical signals from the surface to fire the guns. In more highly deviated wells, coiled tubing may be used. Newer technologies allow the guns to be run on slickline. No communication with the surface is possible with slickline. Instead, a mechanism on the gun arms the charges upon reaching a certain temperature and pressure. A timer will then fire them following a set interval.

The benefit of this strategy is greater deal of control of the well. Casing the bottom of the hole allows the well to be completed without having to worry about reservoir fluids. It also allows precise selection of where in the formation production will be and to be able to seal off perforations, which are no longer useful or counterproductive, through cementing or straddling.

The disadvantage is that perforating can lead to "skin damage", where debris from the perforations can hinder productivity of the well. In order to mitigate this, perforating is commonly done underbalanced (lower pressure in the well bore than in the formation) as the higher formation pressure will caused a surge of fluids into the well at the point of perforating, hopefully carrying the debris with it. Other methods of stimulation such as acidising and proppant fracturing are often required to overcome this damage and bring the well up to its full potential.

Casing and perforating as a method of completion is common place nowadays, though in some unconsolidated formations, prone to production of sand ( BP Harding as an example), open hole completions, using only sandscreens, may be the preferred choice.