The PGA Championship (sometimes referred to as the U.S. PGA Championship outside of North America) is an annual golf tournament conducted by the Professional Golfers Association of America as part of the PGA Tour. The PGA Championship is one of the four major championships in men's golf, and it is the golf season's final major, played in August (customarily the 4th weekend after the Open Championship (British Open), but being advanced a week in 2007 and 2008 because of local scheduling conflicts). Because of its distinction as the season's final major, the PGA Championship is nicknamed "Glory's last shot". It is an official money event on the PGA Tour, the European Tour, and the Japan Golf Tour, with a purse in 2007 of $7 million.

In line with the other majors, winning the PGA gives a golfer several privileges which make his career much more secure, if he is not already one of the elite of the sport. PGA champions are automatically invited to play in the other three majors (the Masters, U.S. Open, and the Open Championship) for the next five years, and are exempt from qualifying for the PGA Championship for life. They also receive membership on the PGA Tour for the following five seasons and invitations to the Players Championship for five years.

The PGA Championship has been held at a large number of venues, some of the early ones now quite obscure, but currently it is usually staged by one of a small group of celebrated courses, each of which has also hosted several other leading events.