The Nikon F4 is a 35mm autofocus (AF) SLR camera first introduced in 1988 as the next generation in Nikon's line of F series professional cameras, designed by Giorgetto Giugiaro. It is one of Nikon's most versatile professional models, able to accept any of Nikon's MF or AF lenses from 1959 to present, including the two F3AF lens (in Autofocus mode).

While it will accept most lenses made for the F mount system, its lack of electronic aperture control limits its functionality with any lens after the D series. The D series and all lenses prior to it have a mechanical aperture ring, where the DX, G, and S series do not. The F4 was introduced as the prior professional model, the Nikon F3, (a manual focus camera) continued in production. The F4 introduced many Nikon owners to autofocus, and was the first professional Nikon to utilize a vertical-travel metal-blade shutter. Though complex, its high-quality mechanical, electronic components and weathersealing made for a reliable and long-lived professional SLR camera.

Eventually Nikon had three F4 models that were distinguished by which integrated battery pack was attached. All F4 bodies are interchangeable with all battery packs:

Nikon introduced its next flagship model, the _F5, in 1996. All F4 models were discontinued soon after in May 1997 http://cameraquest.com/nikonslr.htm. Today, prices of the F4 have depreciated greatly, mainly due to digital camera popularity and obsolescing by the F5 and F6.

Still, the F4 retains some level of popularity among collectors and those who are resistant to using digital cameras as a relatively inexpensive professional level camera. Its high frame rate, quicker than average autofocus system, weather resistant sealing, and fully mechanical aesthetics (including the shutter speed dial) make this a desirable film camera.