The National Institute of Mental Health (NIMH) is part of the federal government of the United States and the largest research organization in the world specializing in mental illness. It is one of the 27 component organizations of the National Institutes of Health (NIH), which is in turn part of the U.S. Department of Health and Human Services. It was formally established in 1949 and research is conducted at a central campus in Bethesda, Maryland, as well as being funded throughout the United States. The stated mission of NIMH is to reduce the burden of mental illness and behavioral disorders through ('biomedical') research on mind, brain and behavior. NIMH is particularly known for studies of genetics, neuroscience and clinical trials of psychiatric medication.