A platinum blonde actress, Natalie Moorehead entered in films in 1929; by end of the following year, she had made dozens of credited movies. Moorehead was more effective with vampish roles, notably a role which she played a suspect in Thin Man, The (1934). Moorhead also made a mark as a comic actress in Hook, Line and Sinker (1930) and Parlor, Bedroom and Bath (1931). She later appeared in supporting roles until the mid-1940s.