Naples is a city in Collier County, Florida, USA. As of 1 July 2006, the U.S. Census Bureau estimated the city's population at 21,804. Naples is a Principal City of the Naples-Marco Island, Florida Metropolitan Statistical Area, which had an estimated total population of 314,649 on 1 July 2006. Despite being the largest city in Collier County, the city of Naples is not its county seat; rather the county seat is located east of the city in unincorporated East Naples.