Nancy Wickwire (November 20, 1925 - July 10, 1974) was an American actress known for roles on several daytime soap operas.

She appeared on Guiding Light (Lila Taylor Kelly, 1954-55), As the World Turns (Claire English Lowell, 1960-64), Another World (Liz Matthews, 1969-71), and Days of Our Lives (Phyllis Anderson, 1972-73).

In addition, she made guest appearances on a number of primetime series, including Route 66, Gunsmoke, The Fugitive, and Ironside. Her last appearance was in a 1973 episode of Barnaby Jones.

She died of cancer in San Francisco, California on July 10, 1974, aged 48.