The Mississinewa River is a tributary of the Wabash River in eastern Indiana and a small portion of western Ohio in the United States. It is about 100 mi (160 km) longblank">http://www.bartleby.com/69/64/M08264.html. Via the Wabash and _Ohio Rivers, it is part of the Mississippi River watershed.

During the War of 1812, the river was the site of the Battle of the Mississinewa, which pitted United States forces against the Miami Indians. Two oilers of the U.S. Navy have been named USS Mississinewa after the river.