Jonny Quest vs. The Cyber Insects is a 1995 telefilm by TNT and Hanna-Barbera. Released on November 19, 1995, it was the final iteration of classic Quest. The film was made as part of a "Year of Jonny Quest" campaign with The Real Adventures of Jonny Quest. The film helped calm certain fans' criticisms of Jessie's introduction to the team of Real Adventures. The Atlanta Journal-Constitution declared Jessie to be "no 'icky girl'...Not only does she save Jonny's life when disturbingly large fire ants attack, but she also teaches him patience." A test screening of Cyber Insects to 30-35 year old males revealed that though some questioned her addition, most "understood that just like the [original] series, [the update] is a reflection of its times." Jonny's original voice actor, Tim Matheson, returned as the voice of 4-DAC. When the movie began, the alternate title was called Jonny's Global Impact.

Tim Matheson (I), who was the voice for the original Jonny Quest, provides the voice for 4-Dac.