Rambo is a character from a series of popular action films starring Sylvester Stallone, based on the characters created by David Morrell in his novel First Blood.

The films featuring the character are: First Blood (1982), Rambo: First Blood Part II (1985), Rambo III (1988), and Rambo (2008). The films focus on a troubled Vietnam War veteran and Green Beret, John James Rambo, who is greatly skilled in all aspects of survival, weaponry, hand-to-hand combat and guerrilla warfare.

Morrell says that in choosing the name Rambo he was inspired by "the sound of force" in the name of the Rambo apples which he encountered in Pennsylvania, and he felt that its pronunciation was similar to the surname of Arthur Rimbaud, the title of whose most famous work A Season in Hell, seemed to him " an apt metaphor for the prisoner-of-war experiences that I imagined Rambo suffering."

In popular culture, the name has become an eponym for a tactic of military aggression or, alternatively, a person demonstrating heroism through extreme violence, especially when outnumbered. However, the term can also be used somewhat derogatorily to describe someone who thoughtlessly charges into a fight with no regard for personal safety or careful planning. This term is commonly referred to as "Going Rambo".

RAMBO (an acronym for "Right After the Manhattan Bridge Overpass" ) refers to a small neighborhood in the downtown area of the New York City borough of Brooklyn. Its borders are Flatbush Avenue Extension, Tillary Street, and the Brooklyn-Queens Expressway (BQE). The only eatery in RAMBO is a 24-hour McDonald's. RAMBO used to be part of Vinegar Hill until the 1950s, when the construction of the BQE effectively isolated it from surrounding areas.