John H. Francis Polytechnic High School is a secondary school located in Los Angeles, California, United States.

Polytechnic, which serves grades 9 through 12, is a part of the Los Angeles Unified School District. Despite its name, Polytechnic is a comprehensive high school.

The school is located in the Sun Valley section of Los Angeles, in the San Fernando Valley. It offers a Magnet program for those willing to attend college in the near future.