Note: James Noble is also the name of an early settler of Ohio.

James Noble (December 16, 1785-February 26, 1831) was the first U.S. Senator from the U.S. state of Indiana.

Noble was born near Berryville, Virginia and moved with his parents to Campbell County, Kentucky when he was 10. There he studied law and he became an attorney, after which he moved to Indiana and settled in Brookville around 1808.

Once settled in Indiana he became a ferryboat operator, a judge and a member of the state's first constitutional convention, in 1816, as a delegate from Franklin County.

He was elected to the first session of the Indiana State House of Representatives in 1816.

He was elected as a Democratic Republican (later an anti-Jacksonian Democrat) to the United States Senate in 1816. He was reelected to two more terms and served from December 11, 1816, until his death in 1831.

While in the Senate he was chairman of the U.S. Senate Committee on Pensions for the 15th, 16th, 17th Congress, 18th and 20th Congresses, and chairman of the U.S. Committee on the Militia for the 16th and 17th Congresses.

He died in Washington, D.C. and is buried in the Congressional Cemetery.

Noble County, Indiana is named in his honor.

James Noble (born March 5, 1922 in Dallas, Texas) is an American actor best known for his portrayal of the slightly daffy Governor Eugene Gatling on the popular 1980s sitcom Benson. He began his career in Soap Operas, most notably, The Brighter Day; As the World Turns and A World Apart. In 1985 he appeared as King Rupert in the Faerie Tale Theatre production of Cinderella.

James Noble (born August 14, 1963 in Jacksonville, Texas) is a former American football wide receiver in the National Football League for the Washington Redskins and the Indianapolis Colts. He played college football at Stephen F. Austin State University.

The son of a Dallas wholesale coal dealer, Noble spent much of his youth attending pool halls and movie houses. He retained his expertise with a pool cue throughout his life, while his stronger interest in acting (fueled by movies) manifested itself in local stage productions and drama studies at Southern Methodist University. Following Navy service in World War II, Noble went to New York to study at the Actors Studio, then went on to a stage revival of Pygmalion wherein he met his future wife, actress Carolyn Coates. The actor appeared on such TV soap operas as "As the World Turns" (1956), "World Apart, A" (1970) and such Broadway productions as 1776 (a role he took to the movie 1776 (1972)), spending much of his spare time in psychotherapy to handle his ongoing feelings of self-doubt. In films from the mid '70s, Noble principally played small roles as authority figures and politicians (Being There (1979), Nude Bomb, The (1980)), with occasional larger roles such as Bo Derek's father in 10 (1979). In 1981 Noble was cast as the genially absent-minded Governor Gene Gatling on the sitcom "Benson" (1979), a role in which he remained until the series' 1986 cancellation. Two years later, he resurfaced on TV in the role of a Nebraska-based recording engineer on the very short-lived sitcom _"First Impressions" (1988).