Isidore Newman School is a private, nondenominational, co-educational college preparatory school located on an 11-acre campus in the Uptown section of New Orleans, Louisiana. The school offers comprehensive education for students in grades Pre-kindergarten through 12th grade, organized into Lower, Middle and Upper schools. In fall 2006 the school had a student body of 935 and a faculty of 152, with an average class size of 15 students per class. In 2008, there are 1018 students and 138 faculty. Enrollment is somewhat lower than the enrollment before Hurricane Katrina devastated New Orleans in August 2005. The largest building on campus is the Cotonio Palaestra, which is also the largest athletic facility in the city.

The school was founded in 1903 by Isidore Newman, a New Orleans philanthropist, and opened its doors the following year as the Isidore Newman Manual Training School (the name was changed in 1931). The school's original mission was to provide academic and practical training for the children of the Jewish Orphans Home.

The school is a member of the Independent Schools Association of the Southwest and the National Association of Independent Schools. It is widely regarded as one of the most rigorous college prep schools in the southern United States.

Newman's athletic teams compete in the Louisiana High School Athletic Association. The Greenies are perennial contenders for state championship honors in a wide range of boys' and girls' sports. Newman's forensics program has won numerous state championships and national championships in the National Forensic League, National Catholic Forensic League, and Tournament of Champions.

Billy Fitzgerald, veteran science teacher and baseball and basketball coach at Newman and the school's athletic director, was the subject of a well-received profile by alumnus Michael Lewis entitled Coach: Lessons on the Game of Life (2005; ISBN 0-393-06091-8).