"Inertiatic ESP" is the somewhat cryptic opening song (excluding the introduction) on the Mars Volta album, De-Loused in the Comatorium. Inertiatic refers to the physical state of inertia. The ESP is a phrase created by the band itself, short for Ectopic Shapeshifting Penance-propulsion.

The music video for the single actually begins with the album's intro "Son et Lumiere" and then leads into the song proper and features footage of the band performing live.

Spain's Rolling Stone Magazine called "Inertiatic ESP" the 67th greatest song of the 21st century http://pub37.bravenet.com/forum/3172289350/show/598247.