Grey Brydges, 5th Baron Chandos (c. 1580 - 10 August, 1621). He was the only son of William Brydges, 4th Baron Chandos and Mary Hopton.

He become Lord Lieutenant of Gloucestershire and was called the "king of the Cotswolds", owing to his generosity and his magnificent style of living at his residence, Sudeley Castle. He has been regarded by Horace Walpole and others as the author of some essays, Horae Subsecivae.

On February 28, 1607, he married Lady Anne Stanley, daughter of Ferdinando Stanley, 5th Earl of Derby and Lady Alice Spencer. His wife was heiress presumptive to the throne of England. However, she was passed over for James VI of Scotland. The couple had the following five children:

• Hon. Robert Brydges (b. 1611), died young.
• Anne Brydges (b. 1612), she did marry, however, little is known as to who and whether there were any issue. There is little evidence about her life.
• Elizabeth Brydges (1619-1678), married her stepbrother, James Tuchet, 3rd Earl of Castlehaven.
• George Brydges, 6th Baron Chandos (1620-1654), married 1. Lady Susan Montagu; 2. Jane Savage. No surviving issue, except for one daughter from his first marriage.
• William Brydges, 7th Baron Chandos (1621-1676), married Susan Kerr. No issue.