Frank von Zerneck (born 1940 in New York City) is an American television producer.

Zerneck's career began as a theater producer in Los Angeles, but moved to television in 1975 in a collaboration with Robert Greenwald, which resulted in the Emmy nominated docudrama 21 Hours at Munich. In 1987 Zerneck and fellow producer Robert M. Sertner created von Zerneck/Sertner Films, a long-term venture which has resulted in nearly a hundred television movies. Of the company's most notable productions are four Native American films produced for Turner Network Television between 1993 and 1996, which included the Emmy winning Geronimo, nominated Crazy Horse, and Golden Globe nominated Lakota Woman. Tecumseh, which concluded the series, was also critically acclaimed. Recent productions have largely consisted of disaster and true crime dramas.