Downtown Miami is the central business district of South Florida, Miami-Dade County and Miami, Florida. Brickell Avenue/Biscayne Boulevard is the main north-south road in downtown, and Flagler Street is the main east-west road in the Central Business District.

Downtown Miami is divided into four distinct areas, Uptown, Park West, the Central Business District and Brickell, and then themselves into many subdistricts. The northernmost area is Uptown, which is divided into the subdistricts of the Omni, Wynwood/Edgewater, and Midtown. To the south of Uptown, is Park West, the Central Business District and south of the Miami River, Brickell, divided into Upper Brickell and Lower Brickell. The CBD is separated from Brickell by the Miami River, NW 7th St marks the line between Park West and the CBD, the Dolphin Expressway separates Park West and Uptown, and Broadway splits Upper and Lower Brickell apart.

Public Transportation in the downtown area is used more than in any other part of Miami and is a vital part of downtown life. The Metromover train system runs 3 lines through downtown (the downtown loop, the Omni loop, and the Brickell loop), and the Metrorail, Miami-Dade County's heavy rail system, makes 3 stops in the downtown area at the Historic Overtown/Lyric Theatre Station, Government Center Station, and the Brickell Station.

The Metrorail has stops throughout Miami as well as Miami-Dade County with connections to Miami International Airport, all Miami-Dade County bus lines, Tri-Rail and Amtrak. The main bus station in downtown is located in Uptown, in the Omni.