The Colville Indian Reservation is an Indian reservation in eastern Washington State, inhabited and managed by Confederated Tribes of the Colville Reservation, which is recognized by the United States of America as an American Indian Tribe. The reservation is located in the southeastern section of Okanogan County and the southern half of Ferry County, but there are pieces of trust land throughout Eastern Washington, including lands located in Chelan County, just to the northwest of the city of Chelan.

The Confederated Tribes have 8,700 descendants from 12 aboriginal tribes. The tribes are known in English as: the Colville, the Nespelem, the Sanpoil, the Lake (Sinixt), the Palus, the Wenatchi, the Chelan, the Entiat, the Methow, the southern Okanagan, the Sinkiuse-Columbia, and the Nez Perce of Chief Joseph's Band. The full origins of the Colville Indians are unknown as the actual reservation was named after Col. John Colville of the U.S. Army who served as the local agent. The spoken language of the tribe is a relatively modern creole made up of the several languages shared within the community since the various tribes were gathered into the Reservation.

Outsiders often named the Colville Scheulpi or Chualpay; the French traders called them Les Chaudières ("the kettles") in reference to Kettle Falls.