Carol Mendelsohn (born 1951) is an American TV writer, notable for her work on the crime drama CSI: Crime Scene Investigation.

Mendelsohn grew up in Chicago. She went to Smith College, but later transferred and in 1973 graduated from Cornell University. She then went to the George Washington University Law School and practiced at the Washington, D.C., office of the prominent Los Angeles-based firm Wyman, Bautzer, Rothman, & Kuchel.

Realizing that she did not want to be a lawyer, she enrolled in an American Film Institute class. She moved to Los Angeles and started writing for the movie industry. Her early work included contributions to Hardcastle and McCormick, Stingray and Wiseguy. As producer for Cannell Studios, she worked on The Trials of Rosie O'Neill and Melrose Place.

In 2000 she joined the production of the pilot episode of CSI: Crime Scene Investigation and has been the drama's show runner and executive producer since. She is also a co-creator and executive producer of CSI: Miami and CSI: NY. As part of the CSI team, she was nominated for the Writers Guild of America Award, the Producers Guild of America Award (twice), the Emmy Award (three times) and the Edgar Award.

Is a 1973 graduate of Cornell University.