Burke's Law was a detective series which ran on ABC from 1963 to 1966 and was revived on CBS in the 1990s. The original show starred Gene Barry as Amos Burke, millionaire Los Angeles Chief of Detectives, who was chauffeured around to solve crimes in his Rolls-Royce. The show had stylistic similarities to Barry's previous series, Bat Masterson, in which he had played the debonair dandy Bat Masterson in the Old West. During the opening credits, as the title flashed onscreen, a woman's voice was heard seductively pronouncing the words "It's Burke's Law!" The title also reflected the character Burke's habit of dispensing wisdom to his underlinigs in a professorial manner, e.g. "Never ask a question unless you already know the answer. Burke's Law." In the original series, other characters were Detective Tim Tilson (Gary Conway), Detective Les Hart (Regis Toomey), and Sergeant Ames (Eileen O'Neill). In several episodes Anne Francis appeared as female detective Honey West, which led to a short-lived spin-off series.

In the last season of the original, 1965–1966, the series was retitled Amos Burke, Secret Agent, and only seventeen episodes were broadcast instead of the thirty-two of the first two seasons. In this last season, Burke went to work for a secret government agency, but still drove around in his Rolls, which had been discreetly bulletproofed by the agency. The supporting cast of the earlier seasons was dropped.

The musical score for Burke's Law was largely the work of Herschel Burke Gilbert, whose middle name was coincidentally the same as the character of the series.

In the revival of the show, which ran on CBS from 1994 to 1995, the title again became "Burke's Law" and Burke was back at work as a police detective. In the second incarnation, Burke was assisted by his son, Peter (Peter Barton). The revival, even more than the original program, was widely regarded as being largely camp. The nostalgic revival featured guest appearances by many of Barry's peers from the 1960s Spy-fi genre, including Patrick Macnee (The Avengers), Peter Lupus (Mission: Impossible) and Anne Francis reprising Honey West (albeit renamed "Honey Best").

The role of Amos Burke actually predated Barry's series, having been played by Dick Powell on an episode of The Dick Powell Show in 1961. The first incarnation of the series was produced by Powell's company, Four Star Television.

This brief revival of the 1960s cop thriller continued the adventures of Amos Burke, a senior Los Angeles police officer and millionaire. By now, Burke was a widower with a son, Peter, who was a detective under his command. The revival continued many of the hallmarks of the old show: glamorous backgrounds, convoluted plots and big-name guest stars. Written by Marg Baskin

Amos Burke was a Los Angeles chief of detectives who was also a millionaire with a chauffeur-driven Rolls Royce, a mansion, and a high-wheeling lifestyle. The hallmarks of this series were glamorous, sophisticated settings, unusual twists on formula homicide plotlines, and big-name guest stars. After a couple of seasons, its format was radically revamped. Burke left the police force and became an agent for US Intelligence. At that point, the show's name changed to "Amos Burke--Secret Agent". Burke's adventures were briefly revived in 1994, under the original title. Written by Marg Baskin