Anne Frank: The Whole Story (also known as Anne Frank) was a mini-series based on the book Anne Frank: The Biography by Melissa Müller. The mini series was shown on American Broadcasting Company on May 20th, 2001. Controversially, but in keeping with the claim made by Melissa Müller, the series asserted that the anonymous betrayer of the Frank family was the office cleaner, when in fact the betrayer's identity has never been established. A disagreement between the producers of the mini-series and the Anne Frank Foundation about validity of this and other details led to the withdrawal of their endorsement of the dramatisation, which prevented the use of any quotations from the writings of Anne Frank appearing within the production. Hannah Taylor-Gordon received both Golden Globe and Emmy Award nominations for her performance as Anne Frank, while Ben Kingsley won a Screen Actor's Guild Award for his performance as Otto Frank, Anne's father.

The façade for an entire block was built on the water in Prague for the Prinsengracht set.

Due to the limited amount of time to use the set, two cameras were used to shoot the beach scene.

In preparation for one of the dream sequences, Hannah Taylor-Gordon (Anne Frank) took ice skating lessons, though she did have a stunt double for the more challenging skating moves.

Hannah Taylor-Gordon's siblings appear as extras.

Scenes were set up so photographs could be taken on the set, such as the Franks' wedding and Anne at a desk.

Steven Spielberg was to be the executive producer, but declined after receiving a letter from Anne Frank's relatives asking him not be involved with the project because it was not based on the authorized account of Franks' life.

The ABC project was not sanctioned by Bernd Elias, Anne Frank's cousin and chairman of the Anne Frank Fonds (which owns copyright of Anne's Dairy), as a result, the film cannot directly quote "Anne Frank: The Diary of a Young Girl".

All four female leads, Anne (Hannah Gordon-Taylor), her sister Margot (Jessica Manley), her mother (Tatjana Blacher) and Auguste Van Pels (Brenda Blethyn) all agreed to lose their hair for the scenes in the concentration camp.