Alessandro Profumo (born February 17 1957) is an Italian banker, the CEO of the Gruppo Unicredito, Italy's major banking group.

Profumo was born in Genoa.

He graduated in business management at the Università Bocconi, he then started working at the Banco Lariano, where he remained from 1977 to 1987. He left the banking activity to enter the sector of business consulting. He was in McKinsey from 1987 to 1989 and in Bain, Cuneo e associati from 1989 to 1991. He went back to the world of credit in April 1991 when he became an important manager for Ras. In 1994 he passed to the Credito Italiano, just one year after the banking group had been privatized. Here he became general director in 1995 and CEO in 1997. When the Gruppo Unicredito was born, in 1998, he became the leader of the new group.

Profumo is also vice president and board member of the ABI, Italian Banking Association.