Are a range of retail outlets which share a brand and central management, usually with standardized business methods and practices.

These characteristics also apply to chain restaurants and some service-oriented chain businesses. Some argue that the standardized products which result from such centralization are culturally detrimental; for example, chain music stores are frowned upon by some for stocking works of more popular music if they exclude less well known, usually independent artists. Critics of chains allege that they are economically damaging to communities because they extract capital that otherwise would recirculate in the local economy with independently owned businesses.

The displacement of independent businesses by chains has generated controversy in many nations and has sparked increased collaboration among independent businesses and communities to prevent chain proliferation. Such efforts occur within national trade groups such as the American Booksellers Association and Council of Independent Restaurants of America as well as community-based coalitions such as Independent Business Alliances. National entities like the American Independent Business Alliance and The New Rules Project promote these efforts in the U.S. In Britain, the New Economics Foundation promotes community-based economics and independent ownership.

By 2004, the world's largest retail chain, Wal-Mart, was the world's largest corporation in terms of gross sales.